Tuesday, November 3, 2015

'Super-agers' study may reveal secrets to staying young

Miami (AFP) - Mary Helen Abbott, 77, paints her lips bright pink, still smokes the occasional cigarette, keeps up on all the gossip at the retirement home and wears a short skirt to fitness class.
Regular exercise and a Mediterranean diet are known to help foster healthy aging
She giggles as the aerobics instructor shouts -- "Swagger! Like you are going to meet someone famous!" -- then she and a dozen seniors throw shoulders back, lift their knees high and strut around the exercise studio.
Abbott is what scientists refer to as a "super-ager," and she is taking part in a $3.2 million study that aims to uncover the secrets to staying sharp and healthy into old age.
While some hunt for medications to treat or prevent dementia, others, like University of Miami neuropsychologist David Loewenstein, are interested in why some people are spared altogether.
"I study Alzheimer's disease, but if we want to unlock the mysteries of the brain we also have to know why some people age successfully," said Loewenstein.
The five-year study funded by the National Institutes of Health is open to people age 63 to 100 who have not been diagnosed with dementia, and who are either in good mental shape or have early signs of memory failure, known as mild cognitive decline.
Loewenstein is particularly intrigued with how some people seem to be able to fend off memory loss, whether by genetic, environmental or other means.
He cites studies involving autopsies on people 85 and above -- a population in which about one in three suffers from dementia.
Nearly another third of this age group have post-mortems that reveal significant hallmarks of dementia -- known as plaques and tangles in the brain -- but seemed just fine while alive.
"How can people function at these higher levels? Science has not been able to answer that," said Loewenstein.
"And that is what we are trying to figure out."
- Staying busy - 
Of the 100 people enrolled in Loewenstein's study so far, more than 40 live at East Ridge, a retirement village that resembles a typical suburban neighborhood in south Florida, with wild peacocks roaming beneath the palm trees, people driving around the manicured grounds on golf carts, and rows of single-story homes divided into multiple apartment units.
Such tranquility does not come cheap. Residents must pay $111,000 up front, then a monthly rent of $2,700 or more, depending on the size of their living space.
Soon after arriving seven years ago, Gwen North, a retired kindergarten teacher who appears decades younger than her age of 85, took on the responsibility of running the thrift store.
"I work probably six days a week," she said, happily.  Click here to continue reading.
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